The blood of Channichthyidae, the most phyletically derived notothenioid family, is devoid of haemoglobin (Hb). Three of the 15 channichthyid species retain inactive genomic remnants of the major adult notothenioid α‐globin gene, but have lost the gene encoding adult β‐globin. In an attempt to understand the mutational events leading to loss of globin expression in channichthyids, the organisation of globin genes in red‐bloode...