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Context matters: emotional responses to urban greening interventions depend on city settingNARA Subscribed
Urban green spaces deliver a remarkable range of human health and well-being benefits, and there is substantial, global effort into incorporating urban greening into the design of cities. However, intense competition for space in cities means small interstitial gaps in the urban fabric are being used for many contemporary green spaces, such as planter boxes or raised garden beds. These small urban greening interventions have b...
Farming in the shadows of Rome: A multi‐proxy palaeoenvironmental record from Loch Clunie—PerthshireNARA Subscribed
Roman impacts on local society is a subject of international significance. Loch Clunie, Perthshire, lies only 5.4 km from Inchtuthil, the only Roman legionary fortress in Scotland, and contains two crannogs and a probable lakeside hillfort. Despite this proximity and the likelihood of local–Roman interaction, these sites remain unexcavated. This paper presents palaeoenvironmental evidence for long‐term social‐economic change a...
Making palaeoclimatology research policy‐relevant: Insights and experience from the DECADAL ProjectNARA Subscribed
Quaternary palaeoclimatology uniquely provides insights and new evidence about climate variability trends and extremes prior to the instrumental record; yet, its knowledge is rarely integrated into governmental decision‐making. This opinion piece shares lessons and experience from the UKRI‐funded DECADAL project, which bridges palaeoclimate science and policy through co‐production with UK climate services and policy institutio...
The aetiology of frailty remains unknown. It has been hypothesised that individual differences in epigenetic mechanisms, particularly DNA methylation (DNAm), may help to explain why some individuals become frail while others do not. Relating epigenetic measures to transitions in age-related frailty in individual patients requires longitudinal studies over many years. To overcome this barrier, we study associations between DNAm...
Discovery of a Potent Small Molecule Antagonist of GRPR for the Treatment of PruritusNARA Subscribed
Persistent pruritus (itch) affects the quality of life, and many itch syndromes remain untreatable. Previously, we identified the gastrin-releasing peptide receptor (GRPR) playing a critical role in mediating histamine-independent itch signaling. In this study, we aimed to identify small-molecule GRPR antagonists to treat histamine-independent itch. Starting with the known small-molecule GRPR antagonist PD 176,252, we conducte...
Non‐native pink salmon Oncorhynchus gorbuscha carcasses benefit native benthic macroinvertebratesNARA Subscribed
The invasion of the North Atlantic by pink salmon Oncorhynchus gorbuscha has raised concerns regarding their impact on coastal rivers. Although the influence of marine‐derived nutrients from returning adult O. gorbuscha on rivers in their native range has received much attention, the ecological consequences of invasive O. gorbuscha for ecosystems outside the native range are largely unknown. To investigate the impact on the de...
Biological characterization of a mid‐water salinity maximum intrusion over the Northeast US ShelfNARA Subscribed
Salinity maximum intrusions, subsurface layers of anomalously salty and warm continental slope water moving onto the continental shelf along the thermocline, are recurring features over the Northeast US Shelf and represent an important cross‐shelf exchange mechanism. While their physical characteristics have been described, the biological composition and ecological role of these intrusions remain poorly understood. Here, we co...
Boat strikes injure and kill large numbers of Florida manatees ( Trichechus manatus latirostris ) each year. Management actions taken to mitigate this threat can be potentially enhanced by consideration of manatee cognitive processes. The role of cognition in marine mammal conservation has received little consideration in the literature. Here, we integrate discoveries from laboratory research on auditory sensory processes and...
Conservation (or safe) havens are protected areas where barriers (e.g., fences) separate biodiversity from threatening processes and are being increasingly used to support conservation. Differences between selection pressures inside and outside havens can be anticipated; however, understanding of the evolutionary consequences of these differences is limited, and many changes may be going unnoticed. This hampers assessments of...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
Exploring Marine Mammal Cognition as a Conservation ToolNARA Subscribed
Cognition is an animal's real‐time adaptation system for responding to change. Rapid environmental change, often anthropogenic, is expanding the range and severity of challenges confronting wild animals. Effective conservation requires a multifaceted approach that includes animals' capacities. Large‐brained, long‐lived animals such as marine mammals often have extensive capability to adaptively modify their behavior due to the...