Animals regularly experience periods of food uncertainty due to seasonal changes and environmental variability. Further, the changing climate is leading to more variable weather patterns, which alter environmental conditions, and can result in resource distributions being less predictable in space and time. How animals respond to uncertain conditions, and in particular a changing distribution of food resources, remains largely...

Dissolvable microarray patches (MAP) represent a promising drug delivery platform; however, the absence of standardised protocols for their preclinical evaluation poses a significant barrier to regulatory approval and clinical translation. Physiologically Based Pharmacokinetic (PBPK) modelling is a powerful tool for predicting drug kinetics following MAP application, addressing key challenges associated with in vitro and in vi...

Soil salinity is a significant abiotic stress factor that impedes plant growth and crop yield, particularly in arid and semi-arid regions. Recent reports indicate that 8.7% of soils globally and 20–50% of irrigated soils across all continents are affected by salt. This phenomenon jeopardizes the food security of more than 1.5 billion people worldwide. Numerous studies have elucidated the beneficial effects of diverse microbes...

Maintaining appropriate peatland hydrology, notably through the regulation of the depth to water table (DWT), is crucial for peatland conservation, restoration, and the mitigation of greenhouse gas (GHG) emissions. We assess the long‐term ecological impact of hydrological changes, primarily induced by drainage, in ombrotrophic peatlands across Europe. Our analysis is based on novel palaeoecological data from seven peat cores c...

This paper is a collaborative effort that originated at the International Space Science Institute Workshop on “Physical links between Weather and Climate in Space and the Lower Atmosphere” held 22–26 January 2024. Many scientists attended that workshop and contributed their expertise related to polar vortex impacts on upper atmosphere variability. This paper summarizes well-known and newly reported signatures of polar vortex w...

Multi-omics data integration has been repeatedly discussed as the way forward to more comprehensively cover the molecular responses of cells or organisms to chemical exposure in systems toxicology and regulatory risk assessment. In Canzler et al. (Arch Toxicol 94(2):371–388. https://doi.org/10.1007/s00204-020-02656-y ), we reviewed the state of the art in applying multi-omics approaches in toxicological research and chemical r...

Overfishing not only drastically reduces the number of fish in an exploited population but is also often selective for body size by removing the largest individuals from a population. Here, we study experimentally the evolutionary effects of size‐selective harvesting using whole‐genome sequencing on a model organism, the zebrafish ( Danio rerio ). We demonstrate genomic shifts in the populations exposed to size‐selective harve...