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NARA Subscribed1
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Springer Nature1
Journal
DARU Journal of Pharmaceutical Sciences1
Publication Year
20141
Ebrahim Faghihloo results 1 · Newest (Page 1/1, per page 25)
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Evaluation of antitumor activity of a TGF-beta receptor I inhibitor (SD-208) on human colon adenocarcinomaNARA Subscribed
DARU Journal of Pharmaceutical Sciences · 2014 · Vol. 22 · Issue 1 · Springer
Abolfazl Akbari; Saeid Amanpour; Samad Muhammadnejad; Mohammad Hossein Ghahremani; Seyed Hamidollah Ghaffari; Ahmad Reza Dehpour; Gholam Reza Mobini; Fatemeh Shidfar; Mahdi Abastabar; Ahad Khoshzaban; Ebrahim Faghihloo; Abbas Karimi; Mansour Heidari
Background Transforming growth factor-β (TGF-β) pathway is involved in primary tumor progression and in promoting metastasis in a considerable proportion of human cancers such as colorectal cancer (CRC). Therefore, blockage of TGF-β pathway signaling via an inhibitor could be a valuable tool in CRC treatment. Methods To evaluate the efficacy of systemic targeting of the TGF-β pathway for therapeutic effects on CRC, we investig...
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