Edwards M. A. results 685
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Genetic ancestry proportion influences risk of adverse events from tuberculosis treatment in BrazilNARA Subscribed
Tuberculosis (TB) treatment is highly effective, but response to therapy varies by geography and population subgroups. We assessed differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry according to major genetic ancestry groups (African, European, and Amerindian) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort usi...
We have attempted to re-establish bay scallops to the Virginia, U.S.A. coastal bays and document the dynamics of the restoration effort. Bay scallops ( Argopecten irradians ) once flourished in the eelgrass ( Zostera marina ) of the Virginia coastal bays. Eelgrass wasting disease led to declines, and both eelgrass and scallops were completely lost after a 1933 hurricane. The Virginia Institute of Marine Science (VIMS) led a su...
The economics of mine waste reduction: The case of ore-sandNARA Subscribed
Purpose Conduction system pacing (CSP) is gaining clinical significance owing to its ability to restore a physiological activation sequence in the ventricles. Whilst His bundle pacing producing the most physiological activation is preferable, due to implant complications the selective activation of the left bundle branch (LBB) by LBB area pacing is considered an alternative, offering both a simpler implant and a physiological...
Examining the Impact of Derelict Pots on Blue Crab ( Callinectes sapidus ) Catch and Harvest Within a Recreational FisheryNARA Subscribed
Derelict fishing gear can negatively affect marine ecosystems through mortality in coastal environments. This study explored the impact of derelict and active crab pots on recreational blue crab ( Callinectes sapidus ) catch rates and landings in a Mid‐Atlantic estuary by deploying experimental pots in four habitat strata within three sections of Indian River Bay, DE. The observed environmental covariates, including temperatur...
Adaptive area-wide management for suppressing spruce budworm outbreaks: effectiveness of the early intervention strategyNARA Subscribed
In eastern North America, two main insecticide-based strategies are used to manage spruce budworm ( Choristoneura fumiferana ) outbreaks. The traditional ‘Foliage Protection Strategy’ (FPS) focuses on temporarily reducing defoliation and tree mortality in high-value stands, allowing outbreaks to progress naturally in surrounding areas. The ‘Early Intervention Strategy’ (EIS) is an adaptive, area-wide management approach that t...
Calibration of the species threat abatement and restoration metric's threat abatement component in a Costa Rican landscapeNARA Subscribed
Achieving global conservation policy goals requires the ability to set and measure progress toward science‐based targets for biodiversity. The species threat abatement and restoration (STAR) metric was developed to enable actors to set science‐based targets for species. STAR scores quantify the potential contribution of actions to abate threats and restore habitat to reduce species extinction risk in a particular place and can...
High frequency turbulent data from sonic anemometers and other ancillary information collected at multiple levels on several meteorological flux towers located at two coastal sites are used to study velocity and scalar (temperature and humidity) structure–function parameters over heterogeneous surfaces in an area of complex coastal terrains. Understanding of such parameters has important applications for studies on wave propag...
Lake sturgeon ( Acipenser fulvescens ) growth and longevity estimated from adult capture–mark–recapture dataNARA Subscribed
Effective fishery management policy depends on accurate life‐history data, particularly for harvested species. Longevity is a core life‐history trait that is directly related to annual survival and lifetime reproductive potential, but fish longevity is generally not well documented, particularly for long‐lived species. We used capture–mark–recapture data spanning 44 years as an alternative method to estimate sex‐specific adult...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...