Metal dyshomeostasis in the brain is a key feature of many neuropathologies, including hypoxic and traumatic injury and chronic conditions such as Alzheimer’s and Parkinson’s disease. Ferroptosis is a form of cell death driven by the intracellular accumulation of iron. This is primarily characterised by a loss in endogenous antioxidant capacity and uncontrolled lipid peroxidation. Ferroptosis has been reported to underlie the...

Permafrost thaw is a major potential feedback source to climate change as it can drive the increased release of greenhouse gases carbon dioxide (CO 2 ) and methane (CH 4 ). This carbon release from the decomposition of thawing soil organic material can be mitigated by increased net primary productivity (NPP) caused by warming, increasing atmospheric CO 2 , and plant community transition. However, the net effect on C storage al...