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Strawberry ( Fragaria × ananassa Duch.) is a high-value global crop, yet its productivity is severely constrained by the two-spotted spider mite, Tetranychus urticae Koch. Developing localized economic thresholds is a cornerstone of sustainable Integrated Pest Management (IPM) to mitigate yield losses and reduce acaricide reliance. This two-season field study (2019–2020) investigated the quantitative relationship between T. ur...
Nano-curcumin mitigates aluminum oxide nanoparticle toxicity in Nile tilapia through antioxidant and immune modulationNARA Subscribed
Our study investigated the toxicological effects of aluminum oxide nanoparticles (Al 2 O 3 -NPs) and the potential protective role of dietary nano-curcumin (N-CUR) in juvenile Oreochromis niloticus (30.39 ± 0.05 g) under controlled experimental conditions. It was hypothesized that N-CUR could mitigate the adverse impacts of Al 2 O 3 -NPs on growth, biochemical, oxidative, and histopathological parameters. A total of 180 O. nil...
Whole genome sequencing identifies monogenic disease in 56.1% of families with early-onset steroid-resistant nephrotic syndromeNARA Subscribed
Genetic causes of steroid-resistant-nephrotic-syndrome (SRNS) represent a rapidly growing number of monogenic diseases. The reported diagnostic yield of various studies applying genetic panels and exome-sequencing to diagnose SRNS is usually < 30%. We performed genome-sequencing in a cohort of Egyptian SRNS patients. We recruited 47 SRNS patients belonging to 41 unrelated families [28 males/19 females; median (range): 6 (0.5–2...
Targeting TREM-1 receptors with metformin and pravastatin modulate monosodium iodoacetate-induced osteoarthritisNARA Subscribed
Osteoarthritis (OA), a degenerative joint condition, affects entire joints, including the tissues around it, causing pain, swelling and stiffness. This study explored the combined therapeutic effects of metformin and pravastatin on knee OA induced by monosodium iodoacetate (MIA) in rats. The study encompassed five animal groups ( n = 10 per group) which were allocated as follows: group 1 received 100 µL of sterile saline injec...