Modeling interoccasion variability (IOV) of pharmacokinetic parameters is challenging in sparse study designs. We conducted a simulation study with stochastic simulation and estimation (SSE) to evaluate the influence of IOV (25, 75%CV) from numerous perspectives (power, type I error, accuracy and precision of parameter estimates, consequences of neglecting an IOV, capability to detect the ‘correct’ IOV). To expand the scope fr...

The species pool concept has advanced our understanding for how biodiversity is coupled at local and regional scales. However, it remains unclear how species pool size, the number of species available to disperse to a site, influences community assembly across spatial scales. We provide one of the first studies that assesses diversity across scales after experimentally assembling grassland communities from species pools of dif...

Summary The F e and N biogeochemical cycles play key roles in freshwater environments. We aimed to determine the spatial positioning and interconnections of the N and F e cycles in profundal lake sediments. The gradients of O 2 , NO 3 − , NH 4 + , pH , E h , F e( II ) and F e( III ) were determined and the distribution of microorganisms was assessed by most probable numbers and quantitative polymerase chain reaction. The redox...