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Assessing the impact of climate change on spring discharge using hydrological modelling in Musanze District, RwandaNARA Subscribed
Climate change has far-reaching impacts on water availability globally, with changing precipitation patterns and global warming contributing to increasing scarcity and unreliability of spring water in many regions. Despite this understanding, the implication of climate change on the hydrological system remains limited in certain areas, including the district of Musanze, Rwanda. This study investigates the effects of climate ch...
Quaternary rocks from the East and West Eifel volcanic fields in western Germany are a key suite of intraplate volcanic rocks that can provide insights into volcanism of the Central European Volcanic Province (CEVP) and into continental intraplate volcanism in general. We present a comprehensive dataset for Eifel lavas including isotope as well as major and trace element data for 59 samples covering representative compositions...
The Subantarctic Zone, the circumpolar region of the Southern Ocean between the Subtropical and Subantarctic fronts, plays an important role in air-sea CO 2 exchange, the storage of anthropogenic CO 2 , and the ventilation of the lower thermocline. Here we use a time series from moored platforms deployed between 2011 and 2021 as part of the Southern Ocean Time Series (SOTS) observatory to investigate the seasonality and intera...
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergyNARA Subscribed
Purpose Ongoing angiogenesis renders the tumor endothelium unresponsive to inflammatory cytokines and interferes with adhesion of leukocytes, resulting in escape from immunity. This process is referred to as tumor endothelial cell anergy. We aimed to investigate whether anti-angiogenic agents can overcome endothelial cell anergy and provide pro-inflammatory conditions. Experimental design Tissues of renal cell carcinoma (RCC)...
Microbial organic matter decomposition is a critical ecosystem function, which can be negatively affected by chemicals. Although the majority of organic matter is stored in sediments, the impact of chemicals has exclusively been studied in benthic systems. To address this knowledge gap, we assessed the impact of a fungicide mixture at three concentrations on the decomposition of black alder leaves in the benthic and hyporheic...
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