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The AAPS Journal · 2025 · Vol. 27 · Issue 6 · Springer
QSP models are increasingly being applied to drug development. Calibrating virtual populations (VPops) to clinical data helps explore patient variability, study populations of interest, and predict clinical outcomes for new therapies. In previous work, we have developed the QSP Toolbox, a library of tools and workflows for developing VPops. The aim is to create a VPop that fits clinical data from a variety of sources and with...