Large flying insects precisely control fast maneuvers, a demanding task made more difficult by the limitation that all information between the brain and body is transmitted through a single transmission line, the neck connective. Despite this neuroanatomical structure constraining both the amount and timing of all information between the brain and body, little is known about how severe these bottlenecks are. We sought to under...

The six-minute walk test (6MWT) is a common method to assess submaximal exercise capacity in children and adults with pulmonary arterial hypertension (PAH) and other chronic diseases. There is no guideline specifically for 6MWT in children. In this observational pilot study, we evaluated the impact of procedural variations on the outcome of the 6MWT in the real-world clinical setting at pediatric PAH programs. We collected 6MW...