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Aryl hydrocarbon receptor deficiency leads to sex- and age-dependent colonic dysmotility in miceNARA Subscribed
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in xenobiotic sensing and multiple physiological functions, including intestinal homeostasis. Aging is associated with reduced colonic motility and constipation, but the contribution of AhR to intestinal motor function across sex and age remains incompletely defined. We performed a phenotypic characterization of AhR-deficient (AhR −/− ) and...
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