F. Cabrera results 105
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Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
The occurrence and spatial distribution of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), fragrances, UV filters and photoinitiators were investigated in surface sediments of Nerbioi-Ibaizabal estuary between 2005 and 2013, in 2020. Samples were extracted by focused ultrasound solid–liquid extraction technique and analyzed by gas chromatography coupled with mass spe...
Potential Ecological Risk Index and Metal Fate in a Karstic Tropical Lagoon: Chelem, Yucatan, MexicoNARA Subscribed
Chelem is a karstic lagoon with urban settlements, economic activities, and environmental services, making it highly vulnerable to metal contamination. This study evaluated metal sediment contamination using enrichment factor, geoaccumulation index and ecological risk index across dry, rainy and Nortes seasons. Cadmium and arsenic concentrations exceed the SQuiRTs thresholds for early biota damage. Metal distribution was drive...
Curdlan, a β-1,3/1,6-glucan found in Alcaligenes faecalis ( A. faecalis ) wall, activates innate and humoral immunity. The aim of this study is to evaluate whether pretreated rats with A. faecalis A12C could prevent sepsis disturbances and identify the immunomodulatory mechanisms involved. Experiments occurred in two stages: a survival study with 16 rats randomly divided into septic (SC) ( n = 8) and septic pretreated (SA) ( n...
Plant invasions may alter disease vector abundance by several mechanistic pathways, including modifying microclimates that influence vector survival or changing habitats to influence host use. Here, we used a field experiment and observational data to evaluate multiple mechanistic pathways (tick survival and host abundance) by which plant invasions may alter vector‐borne disease risk using the common disease vector lone star t...
Refining methods for attributing health impacts to climate change: a heat-mortality case study in ZürichNARA Subscribed
Heat-related deaths occur throughout the summer months, peak during heatwaves, and are affected by temperature and exposed populations’ sensitivities to meteorological conditions. Previous studies found that climate change is increasing heat-related mortality worldwide. We build on existing epidemiological methods to shed light on the adverse effects of climate change on human health. We address limitations in existing methods...
High Prevalence of Plasmid‐Mediated Quinolone Resistance in Salmonella enterica Serovars Isolated From Surface WaterNARA Subscribed
Considering the increasing reports of Salmonella enterica strains resistant to quinolones, antimicrobials frequently employed as therapeutic agents globally, our goal was to investigate the occurrence of plasmid‐mediated quinolone resistance (PMQR) determinants in S. enterica recovered from natural surface waters in Paraíba state, Brazil. Water samples ( n = 230) were collected monthly in triplicate using modified Moore swabs...