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Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Circulating small extracellular vesicles as blood-based biomarkers of muscle health in aging nonhuman primatesNARA Subscribed
Age-associated loss of muscle mass and function and subsequent mobility decline define poor health outcomes, reduced quality of life, and mortality risk. The rate and extent of aging-related muscle loss varies across older adults. It is challenging to understand the molecular pathogenesis of mobility decline, as anthropometric and imaging techniques, primarily used in muscle function assessment, do not offer much molecular inf...
Remote sensing is a valuable tool for rapid identification of benthic features in coastal environments. Past applications have been limited, however, by multispectral models that are typically difficult to apply when bottom types are heterogeneous and complex. We attempt to overcome these limitations by using a spectral library of remote sensing reflectance (R rs ), generated through radiative transfer computations, to classif...
Effects of microalgal communities on reflectance spectra of carbonate sediments in subtidal optically shallow marine environmentsNARA Subscribed
This study was conducted in subtidal areas around Lee Stocking Island, Bahamas, to investigate how microalgal biomass and community structure affect hyperspectral reflectance of sediments. Hyperspectral reflectance was measured on the surfaces of sediment cores collected from several types of carbonate sediments and habitats. Subsequently, photosynthetic and photoprotective pigments within the microalgae colonizing the top 5 m...
Sediment properties influencing upwelling spectral reflectance signatures: The “biofilm gel effect”NARA Subscribed
Microbial communities often produce copious films of extracellular polymeric secretions (EPS) that may interact with sediments to influence spectral reflectance signatures of shallow marine sediments. We examined EPS associated with microbial mats to determine their potential effects on sediment reflectance properties. Distinct changes in spectral reflectance signatures of carbonate sediments from the Bahamas were observed amo...
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