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Sustainable groundwater management is key to building resilience to hydrological extremes but remains challenging in data-scarce transboundary river basins. In this study, a transboundary, collaborative, physically based groundwater modelling approach has been developed for the Limpopo River Basin (LRB), which is highly vulnerable to floods and droughts. Monitoring data and model results consistently suggest that prolonged wet...
Flowering of Strawberry (Fragaria X ananassa Duch.) Under Supplemental LED Lighting During the Nyctoperiod, with Nitrogen and ChillingNARA Subscribed
Newer light-emitting diode (LED) lighting technology increases the feasibility of inexpensively regulating strawberry ( Fragaria x ananassa Duch.) plant development during propagation to enhance fruit production. Nitrogen fertilization and short-term cold storage also influence flowering and fruit production. Two experiments were designed to develop specific treatment combinations to enhance off-season productivity of both lon...
Purpose Conduction system pacing (CSP) is gaining clinical significance owing to its ability to restore a physiological activation sequence in the ventricles. Whilst His bundle pacing producing the most physiological activation is preferable, due to implant complications the selective activation of the left bundle branch (LBB) by LBB area pacing is considered an alternative, offering both a simpler implant and a physiological...
Radiopaque microsphere-hydrogel composite for extended-release intratumoral immunotherapy in a large animal modelNARA Subscribed
Intratumoral injection of immune stimulants could potentially reverse the immunosuppressive tumor microenvironment, but the injected drug rapidly washes out into the systemic circulation. This results in systemic toxicity, and reduced efficacy, potentially requiring daily injections to generate an antitumor immune response. To address this problem, we developed an extended-release hydrogel that retains the immunotherapy agent...
The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry DiagonalNARA Subscribed
Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species, such as many Neotropical frogs. Herein, we conduct a mitochondrial phylogenetic stu...
Lake sturgeon ( Acipenser fulvescens ) growth and longevity estimated from adult capture–mark–recapture dataNARA Subscribed
Effective fishery management policy depends on accurate life‐history data, particularly for harvested species. Longevity is a core life‐history trait that is directly related to annual survival and lifetime reproductive potential, but fish longevity is generally not well documented, particularly for long‐lived species. We used capture–mark–recapture data spanning 44 years as an alternative method to estimate sex‐specific adult...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Accessing crop genetic diversity via pangenomicsNARA Subscribed
With the increasing accuracy and decreasing cost of sequencing technology, the extent of structural variation (SV) and its importance in crop species has become increasingly evident. SVs such as insertions, deletions, and inversions have been associated with genetic variation of agronomically important traits and the diversification of crop species. Pangenomes aim to capture the genetic diversity of a species, population or ge...
New Guinea, the most botanically diverse island on the planet, is the location for one of the boldest conservation initiatives. The Manokwari Declaration aims to achieve 70% conservation designation for the Bird's Head Peninsula. This is 40% higher than the 2022 Global Biodiversity Framework target. However, there is a lack of species occurrence data to support evidence of where biodiversity can be best protected. To address t...