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Veterinary Research Communications · 2023 · Vol. 47 · Issue 4 · Springer
The objective of this study was to use a sensor-based accelerometer (ACC) to identify changes in lying, rumination, and activity times in weaned calves during the moving and regrouping process. Overall, 270 healthy Holstein calves (from approximately 16 regrouping events) at the age of approximately 4 months were enrolled and equipped with an ear-attached ACC (SMARTBOW, Smartbow GmbH/ Zoetis LLC). Sensor data were recorded for...
Medicinal Chemistry Research · 2023 · Vol. 32 · Issue 11 · Springer
The GABA transporter 3 (GAT3) is a member of the GABA transporter (GAT) family proposed to have a role in regulating tonic inhibition. The GAT3-preferring substrate ( S )-isoserine has shown beneficial effects in a mouse model of stroke accompanied by an increased GAT3 expression, indicating a molecular mechanism mediated by GAT3. However, ( S )-isoserine is not ideally suited for in vivo studies due to a lack of selectivity a...