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Contrasting Patterns of Genetic Isolation Among Diadromous, Landlocked, and Non‐Migratory Gobiid Fish PopulationsNARA Subscribed
Dams can landlock populations of amphidromous fishes that formerly migrated between rivers and seas. However, the genetic consequences of these life‐cycle changes remain unclear. Rhinogobius is a speciose genus of freshwater gobies widely distributed in Asia, including non‐migratory R. duospilus and facultatively amphidromous R. similis . Using genome‐wide SNPs from Hong Kong, southern China, we compared the genetic diversity...
Toward a network perspective in coastal ecosystem managementNARA Subscribed
There is an urgent need for countries to transition their national food and land-use systems toward food and nutritional security, climate stability, and environmental integrity. How can countries satisfy their demands while jointly delivering the required transformative change to achieve global sustainability targets? Here, we present a collaborative approach developed with the FABLE—Food, Agriculture, Biodiversity, Land, and...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Betanodavirus : Dissection of the viral life cycleNARA Subscribed
Progressive research has been recently made in dissecting the molecular biology of Betanodavirus life cycle, the causative pathogen of viral encephalopathy and retinopathy in economic important marine fish species. Establishment of betanodavirus infectious clone allows the manipulation of virus genome for functional genomic study, which elucidates the biological event of the viral life cycle at molecular level. The betanodavir...
The approaches of transcriptomic and proteomic have been widely used to study host–pathogen interactions in fish diseases, and this is comparable to the recently emerging application of metabolomic in elucidating disease‐resistant mechanisms in fish that gives new insight into potential therapeutic strategies to improve fish health. Metabolomic is defined as the large‐scale study of all metabolites within an organism and repre...
The mechanisms through which brown‐marbled grouper accomplishes resistance to infection, particularly against Vibrios , are not yet fully understood. In this study, brown‐marbled grouper fingerlings were experimentally infected with Vibrio parahaemolyticus, to identify disease resistance grouper, and the serum proteome profiles were compared between resistant and susceptible candidates, via two‐dimensional gel electrophoresis...
The gram‐negative bacterium, Vibrio alginolyticus , has frequently been identified as the pathogen responsible for the infectious disease called vibriosis. This disease is one of the major challenges facing brown‐marbled grouper aquaculture, causing fish farmers globally to suffer substantial economic losses. The objective of this study was to investigate the proteins involved in the immune response of brown‐marbled grouper fi...