Nickel pollution adversely affects human health and causes various disorders, mainly hepatic and renal dysfunction. The present work focused on a comparative evaluation of the pure form of curcumin (CU) with curcumin-encapsulated chitosan nanoconjugates (CS/CU NCs), on mitigation of the delirious effects of Ni on hepatorenal tissue. Forty-two male rats were allocated into 6 groups (n = 7 for each) as follows: (1) control, (2)...

Nickel is recognized as an environmental contaminant and can affect various living organisms; therefore, clarifying the mechanism of Ni-induced toxicity and elucidating a protection strategy are crucial. This study investigated the neurotoxic potential of dosing nickel sulfate (Ni) on rats and the possible protective mechanism of curcumin in alleviating brain injury. Twenty-eight male albino Wistar rats were allocated into fou...