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Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
Impact of dispersion correction in DFT-enhanced anisotropic NMR for stereochemical elucidation of flexible marine natural productsNARA Subscribed
Although anisotropic NMR spectroscopy has emerged as a powerful method for determining the relative configuration of complex natural products, major challenges persist with structurally flexible molecules. In this study, we conducted a systematic comparative analysis of stereochemical elucidation, combining anisotropic NMR spectroscopy and density functional theory (DFT) calculations on spiroepicoccin B ( 1 ) and epicoccin V (...
The Microphytobenthos are Abundant and Mediate Key Carbon Fluxes in Tropical MangrovesNARA Subscribed
The microphytobenthos (MPB) are known to play important ecological roles in estuarine ecosystems. While tidal flat MPB are widely studied, mangrove MPB are often overlooked due to the common belief that the light-limited environment under the mangrove canopy is not conducive to MPB growth. We assessed the biomass and community characteristics of the MPB in two contrasting mangrove forests (silty substrate and brackish influenc...
The loss of cardiac SIRT3 decreases metabolic flexibility and proteostasis in an age-dependent mannerNARA Subscribed
SIRT3 is a longevity factor that acts as the primary deacetylase in mitochondria. Although ubiquitously expressed, previous global SIRT3 knockout studies have shown primarily a cardiac-specific phenotype. Here, we sought to determine how specifically knocking out SIRT3 in cardiomyocytes (SIRTcKO mice) temporally affects cardiac function and metabolism. Mice displayed an age-dependent increase in cardiac pathology, with 10-mont...