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The subfamily Aleocharinae (Coleoptera: Staphylinidae) comprises the most diverse lineage of beetles associated with eusocial insects, yet a large portion of its termitophilous diversity remains undocumented, particularly in the Neotropical region. Here, we describe Guaranguera zilbermani gen. et sp. n., a new termitophilous rove beetle discovered in nests of Cornitermes cumulans (Kollar, 1832) (Termitidae: Syntermitinae) in s...
Key factors of the deranged antiviral response in elderly patients with COVID-19: a machine-learning analysisNARA Subscribed
Age is a well-known risk factor to develop severe viral respiratory infections, including severe COVID-19. This study aimed to identify the biological alterations linked to severe disease in elderly patients with COVID-19. For this purpose, we employed a derivation cohort with 450 SARS-CoV-2 infected and unvaccinated patients admitted to hospital wards and a validation cohort with 244 SARS-CoV-2 infected and unvaccinated patie...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Aim Microbiome rewilding seeks to harness plant‐microbe interactions for sustainable agriculture, assuming that ancestral microbial partners have been lost during domestication and geographical spread. Designing microbiome rewilding strategies requires a quantitative and predictive understanding of the fundamental ecological processes—selection, dispersal, and drift—driving microbial assembly and persistence in the rhizosphere...
Alzheimer’s disease (AD) is characterized by an insidious onset and complex pathophysiology, necessitating the development of effective strategies for early detection and intervention. This exploratory study aimed to identify differentially expressed genes (DEGs) and disrupted molecular pathways in AD by analyzing blood samples from participants recruited in Valle del Cauca, Colombia, a region with high genetic admixture and p...
Anthropogenic activities have a profound impact on ecosystems, threatening species and contributing to increased extinction rates. Among them are some Leporidae species, for which ecological data remains insufficient to support effective conservation. This study aimed to monitor the status of the volcano rabbit ( Romerolagus diazi ), eastern cottontail ( Sylvilagus floridanus ), and Mexican cottontail ( Sylvilagus cunicularius...
While reef resilience is widely studied, there is increasing recognition of the need to assess it through carbonate production estimates. This study investigated gross carbonate production on Heron Reef (southern Great Barrier Reef) over a 20-year period, examining responses to environmental disturbances and the role of key benthic taxa. Drawing on data from over 30 sites across four geomorphic zones, we identified branching A...
Exploring cadmium bioaccumulation and bioremediation mechanisms and related genes in soil microorganisms: a reviewNARA Subscribed
Cadmium (Cd) is a highly toxic heavy metal that poses serious environmental and health risks. It reduces soil fertility and can cause renal failure, liver damage, bone fractures, hypercalciuria, and cancer in humans. Cd contamination in soil, originating from both natural and human activities, is especially concerning because it bioaccumulates in plants, entering the food chain and affecting crops like tomatoes, rice, cocoa, a...