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NARA Subscribed2
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Springer Nature2
Journal
✓Human Genetics2
Publication Year
20241
20231
F.R. Lin results 2 · Newest (Page 1/1, per page 25)
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Journal: Human Genetics ×Author: F.R. Lin ×Clear All Filters
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A methodology for gene level omics-WAS integration identifies genes influencing traits associated with cardiovascular risks: the Long Life Family StudyNARA Subscribed
Human Genetics · 2024 · Vol. 143 · Issue 9-10 · Springer
Sandeep Acharya; Shu Liao; Wooseok J. Jung; Yu S. Kang; Vaha Akbary Moghaddam; Mary F. Feitosa; Mary K. Wojczynski; Shiow Lin; Jason A. Anema; Karen Schwander; Jeff O. Connell; Michael A. Province; Michael R. Brent
The Long Life Family Study (LLFS) enrolled 4953 participants in 539 pedigrees displaying exceptional longevity. To identify genetic mechanisms that affect cardiovascular risks in the LLFS population, we developed a multi-omics integration pipeline and applied it to 11 traits associated with cardiovascular risks. Using our pipeline, we aggregated gene-level statistics from rare-variant analysis, GWAS, and gene expression-trait...
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Migraine, chronic kidney disease and kidney function: observational and genetic analysesNARA Subscribed
Human Genetics · 2023 · Vol. 142 · Issue 8 · Springer
Wenqiang Zhang; Li Zhang; Luo Yang; Chenghan Xiao; Xueyao Wu; Peijing Yan; Huijie Cui; Chao Yang; Jingwei Zhu; Xuan Wu; Mingshuang Tang; Yutong Wang; Lin Chen; Yunjie Liu; Yanqiu Zou; Ling Zhang; Chunxia Yang; Yuqin Yao; Jiayuan Li; Zhenmi Liu; Ben Zhang; Xia Jiang; Verneri Anttila; Ville Artto; Andrea C. Belin; Anna Bjornsdottir; Gyda Bjornsdottir; Dorret I. Boomsma; Sigrid Børte; Mona A. Chalmer; Daniel I. Chasman; Bru Cormand; Ester Cuenca-Leon; George Davey-Smith; Irene de Boer; Martin Dichgans; Tonu Esko; Tobias Freilinger; Padhraig Gormley; Lyn R. Griffiths; Eija Hämäläinen; Thomas F. Hansen; Aster V. E. Harder; Heidi Hautakangas; Marjo Hiekkala; Maria G. Hrafnsdottir; M. Arfan Ikram; Marjo-Riitta Järvelin; Risto Kajanne; Mikko Kallela; Jaakko Kaprio; Mari Kaunisto; Lisette J. A. Kogelman; Espen S. Kristoffersen; Christian Kubisch; Mitja Kurki; Tobias Kurth; Lenore Launer; Terho Lehtimäki; Davor Lessel; Lannie Ligthart; Sigurdur H. Magnusson; Rainer Malik; Bertram Müller-Myhsok; Carrie Northover; Dale R. Nyholt; Jes Olesen; Aarno Palotie; Priit Palta; Linda M. Pedersen; Nancy Pedersen; Matti Pirinen; Danielle Posthuma; Patricia Pozo-Rosich; Alice Pressman; Olli Raitakari; Caroline Ran; Gudrun R. Sigurdardottir; Hreinn Stefansson; Kari Stefansson; Olafur A. Sveinsson; Gisela M. Terwindt; Thorgeir E. Thorgeirsson; Arn M. J. M. van den Maagdenberg; Cornelia van Duijn; Maija Wessman; Bendik S. Winsvold; John-Anker Zwart
Epidemiological studies demonstrate an association between migraine and chronic kidney disease (CKD), while the genetic basis underlying the phenotypic association has not been investigated. We aimed to help avoid unnecessary interventions in individuals with migraine through the investigation of phenotypic and genetic relationships underlying migraine, CKD, and kidney function. We first evaluated phenotypic associations using...
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