Di-n-butyl phthalate (DBP) is a conventional plasticizer known to induce hepatotoxicity and nephrotoxicity through oxidative stress and apoptosis. In contrast, curcumin, a polyphenolic compound from Curcuma longa , has significant antioxidant and anti-apoptotic activity; however, its therapeutic efficiency is limited due to poor absorption and low bioavailability. Nanoliposomes can significantly enhance the stability and absor...

Ursolic Acid (UA), a naturally occurring pentacyclic triterpene, was isolated from Ochrosia elliptica . Polycystic Ovary Syndrome (PCOS) a prevalent endocrine disorder characterized by hyperandrogenism, insulin resistance, and chronic inflammation. In this study, we investigate the role of UA in alleviating the symptoms of PCOS, focusing on its biochemical, hormonal, and histopathological effects in a rat model. Using adult fe...

Our study investigated the toxicological effects of aluminum oxide nanoparticles (Al 2 O 3 -NPs) and the potential protective role of dietary nano-curcumin (N-CUR) in juvenile Oreochromis niloticus (30.39 ± 0.05 g) under controlled experimental conditions. It was hypothesized that N-CUR could mitigate the adverse impacts of Al 2 O 3 -NPs on growth, biochemical, oxidative, and histopathological parameters. A total of 180 O. nil...

Hyalomma dromedarii ( H. dromedarii ) is a major ectoparasite of camels in arid regions such as Egypt, where it causes significant economic losses and transmits several zoonotic pathogens. This study evaluated the acaricidal efficacy of a novel, locally prepared Astragalus polysaccharides nanoemulsified formulation (APS-NE) against various developmental stages of H. dromedarii infesting camels. APS-NE was prepared using ultras...

The current study investigated the effect of a single administration of human chorionic gonadotropin hormone (hCG) and its nanoparticles (NPs) on testicular hemodynamics using Doppler ultrasonography, testicular volume, testicular echotexture (PIX), and circulating testosterone and nitric oxide (NO) in pubescent goat bucks during summer months. Fifteen Baladi goats were divided into three groups (5 in each) and subjected to a...

Environmental heat stress (HS) impairs reproductive efficiency in farm animals. This study investigated, for the first time, how the melatonin and melatonin nanoparticles treatment affected the testicular hemodynamics, testicular volume, echotexture [Pixel intensity (PIX) and integrated density (IND)], scrotal circumference, serum concentration of testosterone (T), estradiol (E 2 ), nitric oxide (NO), and total antioxidant cap...