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Rationale and objectives Glycyrrhiza glabra L. (Fabaceae; licorice) is a widely used medicinal herb known to exert protective effects against multiple neurological diseases. The flavonoid, isoliquiritigenin (ISL), is a main constituent of roots of Glycyrrhiza glabra . ISL has been reported to behave as a GABA B receptor agonist and exert multiple pharmacological effects. Given the role of the GABA B receptor in the neurobiolog...
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