Francesca Luca results 329
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Microglia-derived extracellular vesicles uncover early alterations of inflammatory signaling in Alzheimer’s diseaseNARA Subscribed
Alzheimer’s disease (AD) is increasingly recognized as a neurodegenerative disorder associated with chronic low-grade inflammation and age-related immune dysregulation. Microglial-derived extracellular vesicles (MDEVs) are emerging as important mediators of neuroimmune communication and potential biomarkers reflecting pathological processes occurring within the central nervous system (CNS). However, how EV-associated inflammat...
Institutional coordination in urban citizen science: a case study within the Italian City Nature ChallengeNARA Subscribed
Citizen science is increasingly used to document biodiversity in urban ecosystems while simultaneously promoting public engagement with nature. However, how institutional coordination relates to participation levels and the resulting representation of urban biodiversity remains poorly understood, particularly in European cities. The City Nature Challenge is a global annual bioblitz that engages citizens in recording urban biod...
Age-adjusted leukocyte telomere length predicts long-term mortality in older patients discharged from acute care hospitalsNARA Subscribed
Leukocyte telomere length (LTL) is a widely studied biomarker of biological aging, reflecting cumulative cellular damage beyond chronological age. However, its prognostic relevance in clinically complex populations such as hospitalized older adults remains uncertain. In this prospective observational study, 872 patients aged ≥ 65 years admitted to acute care wards of IRCCS INRCA within the Report-AGE cohort were included. LTL...
Personality differences between native and invasive populations of the eastern gray squirrelNARA Subscribed
Invasive alien species are a major threat to global biodiversity, thus recent work has aimed to identify traits of successful invaders to better inform management efforts and predictions of future invasions. Personality and intraspecific behavioral variation are important characteristics that may mediate individuals’ and species’ invasion success. However, to the best of our knowledge, no study to date has looked at the person...
Inter-session variability of muscle synergies during upper limb elevation movements in healthy subjectsNARA Subscribed
Muscle synergies provide a framework to study motor control in healthy and clinical populations through electromyographic recordings during motor tasks. However, their variability has been poorly investigated. This study aimed to assess inter-session variability of muscle synergies during elevation tasks performed with the dominant and non-dominant upper limbs in healthy subjects. Fifteen young healthy adults performed explosi...