Francesca Marini results 31
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Monitoring Essential Ocean, Climate, and Biodiversity Variables (EOVs, ECVs and EBVs) collected through the marine Research Infrastructures (RIs) is critical for assessing environmental status, improving scientific knowledge and defining environmental policies. This study evaluates the capacity of the Italian marine monitoring system, including facilities such as fixed stations, buoys, autonomous platforms, and mobile systems...
Humans have facilitated the spread and evolution of invasive species, a pattern that has accelerated with the globalisation of trade and societal development. Consequently, the invasiveness of a species may be determined not only by how many propagules and which genotypes are introduced, but also by its evolutionary history and how humans have interacted with it. Here, we document the population structure and movement of Sahar...
Anthracyclines’ cardiotoxicity involves an accelerated generation of reactive oxygen species. This oxidative damage has been found to accelerate the expression of hexose-6P-dehydrogenase (H6PD), that channels glucose-6-phosphate (G6P) through the pentose phosphate pathway (PPP) confined within the endoplasmic/sarcoplasmic reticulum (SR). To verify the role of SR-PPP in the defense mechanisms activated by doxorubicin (DXR) in c...
The immunolocalization of adiponectin and its receptors in the testis of the frog Pelophylax bergeriNARA Subscribed
In all vertebrates, reproductive strategies are achieved by modulation of the neuroendocrine system in a similar manner and with minor variations among the different classes. Most of the available information on amphibian testicular cycles derive from anurans, and among these, water frogs have been extensively studied in terms of reproductive mechanisms and sex steroid correlation. Adiponectin (AdipoQ) and its receptors—AdipoR...
Few studies have evaluated the association between circulating levels of 25-hydroxyvitamin D (25(OH)D), 1,25-dihydroxyvitamin D (1,25(OH) 2 D), and the endocrine disruptor bisphenol A (BPA), with risk of cardiovascular (CV) disease in elderly individuals. This was a cross-sectional study in a subgroup of elderly people from the InCHIANTI Biobank in Italy. We examined the association between circulating serum vitamin D metaboli...
Copper (Cu) toxicity is a pressing concern for several soils, especially in organic viticulture. The objective of this work was to assess Cu toxicity on the non-target organism Eisenia fetida , employing both traditional and novel tools for early identification of Cu-induced damages. In addition to traditional tests like avoidance and reproductive toxicity experiments, other tests such as the single cell gel electrophoresis (S...
Genotype–phenotype correlation in contactin-associated protein-like 2 (CNTNAP-2) developmental disorderNARA Subscribed
Contactin-associated protein-like 2 ( CNTNAP2 ) gene encodes for CASPR2, a presynaptic type 1 transmembrane protein, involved in cell–cell adhesion and synaptic interactions. Biallelic CNTNAP2 loss has been associated with “Pitt-Hopkins-like syndrome-1” (MIM#610042), while the pathogenic role of heterozygous variants remains controversial. We report 22 novel patients harboring mono- ( n = 2) and bi-allelic ( n = 20) CNTNAP2 va...
A growing attention has been paid to the deep renovation of RC buildings, particularly focusing on their structural vulnerability and on the development of retrofit strategies; however, the issue of the in-plane diaphragm action and the capacity of existing floors has rarely been addressed. Although floor capacity does not seem critical for the seismic capacity of existing structures, commonly affected by greater vulnerabiliti...
NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the NeotropicsNARA Subscribed
Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal specie...