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Springer Nature1
Journal
Immunologic Research1
Publication Year
20241
Francesca Senes results 1 · Newest (Page 1/1, per page 25)
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Author: Francesca Senes ×Clear All Filters
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Pomalidomide in patients with multiple myeloma: potential impact on the reconstitution of a functional T-cell immunityNARA Subscribed
Immunologic Research · 2024 · Vol. 72 · Issue 6 · Springer
Jiaxin Shen; Francesca Senes; Xiaofen Wen; Patrizia Monti; Shaoze Lin; Claudia Pinna; Andrea Murtas; Luigi Podda; Giuseppina Muntone; Gianni Tidore; Claudia Arru; Luca Sanna; Salvatore Contini; Patrizia Virdis; Leonardo Antonio Sechi; Claudio Fozza
Background Pomalidomide, a third-generation oral immunomodulatory drug, exhibits efficacy in patients with relapsed multiple myeloma or those refractory to bortezomib and lenalidomide (RRMM). Methods In this clinical context, we employed flow cytometry and CDR3 spectratyping to monitor the dynamics of the T-cell repertoire during Pomalidomide treatment, aiming to investigate its potential to reverse the immunological abnormali...
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