G. Alexander results 1,097
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Standardized microhaplotype databases and frameworks for assessing and mining crop genetic diversityNARA Subscribed
Keymessage Standardized microhaplotype databases for eight diverse crops enable multiallelic analyses, comparative genetics, and breeding decisions. Abstract Microhaplotypes are short genomic segments that contain multiple tightly linked variants, providing multi-allelic data that can enhance genetic resolution compared to traditional biallelic single nucleotide polymorphism (SNP) markers. Here, we present the creation and uti...
Assessing the statistical significance of structural factors on community resilience during the early phase of the COVID-19 pandemicNARA Subscribed
Empirical evidence on which structural factors reliably shape community resilience during pandemics remains fragmented: existing studies often focus on single dimensions, small indicator sets, or do not test the robustness of identified drivers. Using 401 German administrative districts and a large pool of 266 district-level indicators, we identify structural factors associated with regional COVID-19 impacts across four resili...
Coastal waters are increasingly susceptible to low-oxygen conditions where circulation or nutrient inputs have been altered by anthropogenic activities, leading to increased occurrence of coastal hypoxia worldwide. Low-oxygen conditions also occur naturally in coastal settings, typically in bottom water or landward of sills where circulation is weak. Here we identify and characterize a persistent, low-oxygen layer in the mid-w...
Eucalyptus grandis Auxin Response Factor 10 (EgrARF10) is associated with the modulation of secondary xylem cell wall chemistryNARA Subscribed
Auxin Response Factors (ARFs) are of vital importance in plant growth and vascular development. Class A ARFs are the core auxin-driven drivers of embryogenesis, vascular pattern development, (pro)cambial stem cell initiation and xylem cell fate specification, while class B ARFs may attenuate or fine-tune auxin-mediated development. The potential roles of class C ARFs in vascular development and xylogenesis, however, remain lar...
Longitudinal lipidomic markers of cardiac aging and risk of coronary heart disease in American Indians: the Strong Heart Family StudyNARA Subscribed
Age-related decline in left ventricular (LV) diastolic function is a hallmark of cardiac aging and an early precursor to cardiovascular disease. While dyslipidemia is a known driver of coronary heart disease (CHD), the molecular pathways linking lipid metabolism to cardiac aging and subsequent CHD risk remain poorly understood. Furthermore, longitudinal lipidomic profiling of cardiac aging in large human populations has not be...