Cell fate determination and terminal differentiation are shaped by intrinsic molecular programs that coordinate lineage-specific gene expression. In mesenchymal stem cells (MSCs), variability in osteogenic efficiency among distinct tissue sources remains poorly understood and cannot be fully explained by differentiation conditions alone. Increasing evidence indicates that post-transcriptional regulatory mechanisms, particularl...

Understanding the impact of fractures on fluid flow is fundamental for developing geoenergy reservoirs. Pressure transient analysis could play a key role for fracture characterization purposes if better links can be established between the pressure derivative responses ( p ′) and the fracture properties. However, pressure transient analysis is particularly challenging in the presence of fractures because they can manifest them...

This integrative study examined the morphological and genetic affinities of three endemic barbel species from Italy (brook barbel Barbus caninus , Italian barbel Barbus plebejus and horse barbel Barbus tyberinus ) and of putative hybrid specimens to their species of origin. Two of the species frequently occur together with the non‐native barbel Barbus barbus . DNA barcoding indicates that mitochondrial (mt) haplotypes often do...

Fire shapes the distribution of savanna and forest through complex interactions involving climate, resources and species traits. Based on data from central Brazil, we propose that these interactions are governed by two critical thresholds. The fire‐resistance threshold is reached when individual trees have accumulated sufficient bark to avoid stem death, whereas the fire‐suppression threshold is reached when an ecosystem has s...

Tropical savanna and forest are recognized to represent alternate stable states, primarily determined by feedbacks with fire. Vegetation–fire dynamics in each of these vegetation types are largely determined by the influence of the vegetation on fire behavior, as well as the effects of fire behavior on tree mortality, topkill (defined here as complete death of the aerial biomass, regardless of whether the plant recovers by res...