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3D Texture Analysis of the Corpus Callosum in T1-Weighted MR Images of Children with a Traumatic Brain InjuryNARA Subscribed
Investigating traumatic brain injuries (TBI) in the developing brain is a challenging task. The superposition of an injury to the normal development trajectory can lead to brain impairments which are not obvious at diagnosis. T1-weighted MRI, acquired routinely post-injury, has the potential to better inform diagnosis, but is limited by qualitative assessment by radiologists. Using T1-weighted volume images, we investigated th...
Using pre-release efficacy as a candidate agent prioritisation tool for the weed Trichocereus spachianus (Caryophyllales: Cactaceae)NARA Subscribed
Pre-release efficacy assessments (PREA) can be used to prioritise the most damaging candidate agents for further studies in biological control programmes against invasive alien plants. This study assessed the efficacy of various potential enemies of Trichocereus spachianus (Riccob.) (Caryophyllales: Cactaceae), an invasive cactus in South Africa, in order to prioritise the most damaging candidates for further studies, includin...
Preliminary insights into manta ray (Mobula alfredi and M. birostris) population demographics and distribution in South AfricaNARA Subscribed
Both the reef manta ray, Mobula alfredi and oceanic manta ray M. birostris , are repeatedly observed in South Africa, yet little is known about the distributions of either species. In this study, we collated citizen science observations since 2003 to reveal six areas in the KwaZulu-Natal (KZN) and Eastern Cape provinces, where manta rays have been sighted across multiple years. Using their unique ventral spot patterning, 184 i...
John Raven, FRS, FRSE: a truly great innovator in plant physiology, photosynthesis and much moreNARA Subscribed
This is a tribute to a truly inspirational plant biologist, Prof. John A. Raven, FRS, FRSE (25th June 1941– 23rd May 2024), who died at the age of 82. He was a leader in the field of evolution and physiology of algae and land plants. His research touched on many areas including photosynthesis, ion transport, carbon utilisation, mineral use, such as silicon, iron and molybdenum, the evolution of phytoplankton, the evolution of...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Genomic selection shows improved expected genetic gain over phenotypic selection of agronomic traits in allotetraploid white cloverNARA Subscribed
Key message Genomic selection using white clover multi-year-multi-site data showed predicted genetic gains through integrating among-half-sibling-family phenotypic selection and within-family genomic selection were up to 89% greater than half-sibling-family phenotypic selection alone. Abstract Genomic selection, an effective breeding tool used widely in plants and animals for improving low-heritability traits, has only recentl...
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia predictionNARA Subscribed
DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of cognitive impairment and future dementia risk using the ADNI database. Of several MA algorithms, DunedinPACE and GrimAge2, associated with memory, were combined in a composite MA alongside BA and a data-driven FI in predictive analyse...
An empirical tool for predicting the presence or absence of coseismic displacements at GNSS stationsNARA Subscribed
Unmodeled displacements in GNSS times series, induced by instrumental artifacts or geophysical events, create significant biases in station trajectory parameters that can propagate into the reference frame itself. While non-tectonic ‘jumps’, such as equipment changes, affect only a specific GNSS station, seismically-induced displacements can affect large numbers of sites, severely threatening the frame’s stability. Manually re...
Predator-prey interactions in marine ecosystems control population sizes, maintain species richness, and provide intermediate disturbance. Such ecosystem structuring interactions may be rare in Antarctic epibenthic communities, which are unique among marine ecosystems worldwide for their dominance of soft bodied fauna (sponges, soft and hard corals, and echinoderms) and a simultaneous paucity of shell crushing predators (shark...