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From field to sky: measurement and modeling of transgenic switchgrass pollen dispersal in the atmosphereNARA Subscribed
Accurate tracking and measurement of pollen dispersal in the atmosphere are essential for assessing cross-pollination risks, particularly in the case of genetically engineered (GE) crops. We conducted a series of unique release-recapture field studies with GE switchgrass in Oliver Springs, TN, USA. Two hundred transgenic switchgrass plants ( Panicum virgatum L. “Performer”) were planted at the center of a clear-cut field, with...
There is a growing need for scalable and high-throughput model systems to study plant-pathogen interactions and fungal secondary metabolite production. This research addresses that need by exploring the use of callus culture as a proxy for whole-plant infection dynamics and mycotoxin biosynthesis. Both callus and intact Arabidopsis thaliana plants were inoculated with the fungal pathogen, Fusarium graminearum. Disease progress...
Metabolic Profiles of Encapsulated Chondrocytes Exposed to Short-Term Simulated MicrogravityNARA Subscribed
The mechanism by which chondrocytes respond to reduced mechanical loading environments and the subsequent risk of developing osteoarthritis remains unclear. This is of particular concern for astronauts. In space the reduced joint loading forces during prolonged microgravity (10 −6 g) exposure could lead to osteoarthritis (OA), compromising quality of life post-spaceflight. In this study, we encapsulated human chondrocytes in a...
Responses of a federally threatened shorebird to trophic downgrading and expansion of domestic cats (Felis catus)NARA Subscribed
Along U.S. Atlantic and Gulf Coast barrier islands, red foxes ( Vulpes vulpes ) are top predators that are thought to impact smaller mesopredators and depredate beach-nesting birds. Starting in 2015, sarcoptic mange epizootics among red foxes led to their eventual temporary extirpation from most of Fire Island, NY, USA. We monitored the subsequent changes to the mammalian predator community on this barrier island and explored...
The use of unique markers in ornithology has a long history and is predicated on the assumption that markers have negligible effects on behavior and survival. The assumption that marks are harmless is particularly important with imperiled species. We studied the effects of two different marking schemes on Piping Plovers ( Charadrius melodus ), a small shorebird protected under the U.S. Endangered Species Act that is intensivel...
A framework to support the identification of critical habitat for wide-ranging species at risk under climate changeNARA Subscribed
To recover species at risk, it is necessary to identify habitat critical to their recovery. Challenges for species with large ranges (thousands of square kilometres) include delineating management unit boundaries within which habitat use differs from other units, along with assessing any differences among units in amounts of and threats to habitat over time. We developed a reproducible framework to support identification of cr...
During the “Godzilla” dust storm of June 2020, unusually high fluxes of mineral dust traveled across the Atlantic from the Sahara Desert, reaching the Caribbean Basin, Gulf Coast, and southeastern United States. Additionally, an eruption of the La Soufrière volcano on St. Vincent in April 2021 generated substantial ashfall in the southeastern Caribbean. While many studies have analyzed mineral dust’s ability to relieve nutrien...
Genetic drift drives rapid speciation of an Arctic insular endemic shrew ( Sorex pribilofensis )NARA Subscribed
Episodes of Quaternary environmental change shaped the genomes of extant species, influencing their response to contemporary environments, which are changing rapidly. Island endemics are among the most vulnerable to such change, accounting for a disproportionate number of recent extinctions. To prevent extinctions and conserve island biodiversity it is vital to combine knowledge of species' ecologies with their complex evoluti...
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severityNARA Subscribed
The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the pr...
Gene family expansions and transcriptome signatures uncover fungal adaptations to wood decayNARA Subscribed
Summary Because they comprise some of the most efficient wood‐decayers, Polyporales fungi impact carbon cycling in forest environment. Despite continuous discoveries on the enzymatic machinery involved in wood decomposition, the vision on their evolutionary adaptation to wood decay and genome diversity remains incomplete. We combined the genome sequence information from 50 Polyporales species, including 26 newly sequenced geno...
Harmony on the prairie? Grassland plant and animal community responses to variation in climate across land‐use gradientsNARA Subscribed
Human induced climate and land‐use change are severely impacting global biodiversity, but how community composition and richness of multiple taxonomic groups change in response to local drivers and whether these responses are synchronous remains unclear. We used long‐term community‐level data from an experimentally manipulated grassland to assess the relative influence of climate and land use as drivers of community structure...