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Coastal waters are increasingly susceptible to low-oxygen conditions where circulation or nutrient inputs have been altered by anthropogenic activities, leading to increased occurrence of coastal hypoxia worldwide. Low-oxygen conditions also occur naturally in coastal settings, typically in bottom water or landward of sills where circulation is weak. Here we identify and characterize a persistent, low-oxygen layer in the mid-w...
Precision measurement of the Ds*+-Ds+ meson mass differenceNARA Subscribed
HIV is highly comorbid with cocaine use disorder (CUD). Relapse is a major challenge in the treatment of CUD, and people living with HIV (PLWH) exhibit shorter time to relapse. One driver of relapse may be re-exposure to cocaine, which can be modeled in rodents using cocaine-primed reinstatement. This process involves neuroadaptations within the medial prefrontal cortex (mPFC) and nucleus accumbens (NAc) shell, regions that me...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Flatfishes are important components of benthic communities and support small-scale fisheries that sustain livelihoods in the southwestern Indian Ocean. However, limited data on their diversity and distribution hinder effective management and conservation, especially under growing threats from destructive fishing and climate change. To address this, 134 flatfish specimens from the Tanzanian coast were analyzed. Specimens were i...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Complete genome sequence of citrus tristeza virus isolate PB61, a commercially deployed mild strain for cross-protection in grapefruitNARA Subscribed
Citrus tristeza virus (CTV; species Closterovirus tristezae ) is ubiquitous in Australia, occurring in all production areas. Stem-pitting disease in white grapefruit varieties caused by CTV is managed by mild strain cross-protection. However, the protective isolate of CTV used for cross-protection, labelled PB61, is not fully characterised at the molecular level, even though most grapefruit budwood is inoculated with this viru...
New parajeilongviruses detected in bats but not in humans: assays for screening and diagnostic purposesNARA Subscribed
To enhance preparedness against existing and new zoonotic viruses such as Hendra virus, Nipah virus, and other paramyxoviruses, screening tools and efficient diagnostic methods are needed. Here, we established a conventional nested pan-PCR assay using previously described primers for screening of human and bat samples. Additionally, we developed specific real-time RT-PCR (RT-qPCR) assays to detect Nipah virus and Hendra virus...
Zooplankton diversity in highly urbanized ponds: The role of road salt is not reflected by watershed impervious coverNARA Subscribed
Urban ecosystems are structured by multiple anthropogenic stressors, yet despite the increasing extent and rate of urbanization worldwide, the ecological consequences of excessive road salt application and other urban phenomena remain poorly resolved. To advance understanding of these drivers and their effects on aquatic ecosystems, we collected zooplankton and associated environmental data from 50 permanent stormwater managem...