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Over the past 80 years, tilapia have been translocated globally for aquaculture; active production is recorded in >124 countries. Of 7 million tonnes of tilapia produced in aquaculture, 79% is from 79 countries outside the natural range of tilapia. Capture fisheries account for a further 723,627 tonnes of tilapia, and >47% of this is landed from established invasive populations outside Africa. Tilapias host a rich fauna of par...
A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsisNARA Subscribed
Sepsis is a life-threatening condition driven by the dysregulation of the host immune response to an infection. The complex and interacting mechanisms underlying sepsis remain not fully understood. By integrating prior knowledge from literature using mathematical modelling techniques, we aimed to obtain a deeper mechanistic insight into sepsis pathogenesis and to evaluate promising novel therapeutic targets, with a focus on To...
Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemiaNARA Subscribed
In this study, we describe the kinetics of a new potential inflammatory biomarker, presepsin, together with a panel of well-established biomarkers in a human endotoxemia study. We evaluated biomarker correlations and identified combinations that could hold valuable insights regarding the state of infection.
Microbes in aquifers are present suspended in groundwater or attached to the aquifer sediment. Groundwater is often sampled at gasoline ether oxygenate (GEO)-impacted sites to assess the potential biodegradation of organic constituents. However, the distribution of GEO-degrading microorganisms between the groundwater and aquifer sediment must be understood to interpret this potential. In this study, the distribution of ethyl t...
The ancient B ritons: groundwater fauna survived extreme climate change over tens of millions of years across NW E uropeNARA Subscribed
Global climate changes during the C enozoic (65.5–0 Ma) caused major biological range shifts and extinctions. In northern E urope, for example, a pattern of few endemics and the dominance of wide‐ranging species is thought to have been determined by the P leistocene (2.59–0.01 Ma) glaciations. This study, in contrast, reveals an ancient subsurface fauna endemic to B ritain and I reland. Using a B ayesian phylogenetic approach,...
Sphagnum cuspidatum , S. magellanicum and S. rubellum are three co‐occurring peat mosses, which naturally have a different distribution along the microtopographical gradient of the surface of peatlands. We set out an experiment to assess the interactive effects of water table (low: −10 cm and high: −1 cm) and precipitation (present or absent) on the CO 2 assimilation and evaporation of these species over a 23‐day period. Addit...
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