The main treatment of MM metastases are systemic therapies, surgery, limb perfusion, and intralesional talimogene laherparepvec. Electrochemotherapy (ECT) is potentially useful also due to the high response rates recorded in cancers of any histology. No randomized studies comparing ECT with other local therapies have been published on this topic. We analyzed the available evidence on efficacy and toxicity of ECT in this settin...

Nowadays, policies addressed to prevention and mitigation of seismic risk need a consolidated methodology finalised to the assessment of local seismic response in explosive volcanic settings. The quantitative reconstruction of the subsoil model provides a key instrument to understand how the geometry and the internal architecture of outcropping and buried geological units have influence on the propagation of seismic waves. On...