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Collection, handling and care of cephalopod eggsNARA Subscribed
Research on cephalopod early ontogeny has significantly advanced in recent decades, including embryo organogenesis and neurogenesis and early behavioural adaptations, particularly in commercially important and coastal species. Within this context, here we compiled current knowledge on the collection, handling and care under experimental conditions and monitoring in the field of cephalopod eggs and egg masses. It covers field o...
Ensuring reproducibility in scientific research is crucial for validating findings, advancing knowledge, and fostering trust within the scientific community. Containerization of code is a widespread practice to help ensure reproducibility in neuroimaging research. However, there exists no universal method of sharing containers, nor is it feasible to broadly enforce rules due to the diversity of research practices. We posit tha...
Inter-beach movements and inter-nesting periods of olive ridley sea turtles relate to nesting behavior in a nascent arribada beachNARA Subscribed
Olive ridley sea turtles ( Lepidochelys olivacea ) exhibit two nesting behaviors: solitary nesting and synchronized mass-nesting, known as arribada , with females able to switch between behaviors rather than being exclusive to one strategy. Although arribadas are thought to be driven by environmental and/or social cues that promote synchronized breeding, it remains unclear to what extent they can shape the spatial and temporal...
Marine invertebrates, which comprise 92% of ocean biodiversity, play a crucial role in maintaining healthy and productive ecosystems by shaping habitats and forming part of the foundation of food webs. They also serve as a critical food source sustaining major global fisheries and provide valuable models for biomedical research due to their diverse physiological adaptations. Climate change-driven biodiversity loss threatens bo...
Promoting Research Excellence in Down Syndrome: Proceedings of the 5th International Conference of the Trisomy 21 Research SocietyNARA Subscribed
Down syndrome (DS), or trisomy 21 (T21), represents the most common genetic cause of intellectual disability worldwide and is associated with a wide range of medical, developmental, and neurodegenerative conditions, including a universal predisposition to early-onset Alzheimer’s disease (AD). Since its establishment in 2014, the Trisomy 21 Research Society (T21RS) has provided a global forum for advancing DS research across di...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
Independent neural drives and distinct motor unit discharge characteristics in hamstring muscles during isometric knee flexionNARA Subscribed
Purpose Our study investigated the discharge characteristics of motor units (MUs) in the semitendinosus (ST) and biceps femoris (BF) at three knee-joint angles that varied muscle length. Methods Fifteen males (21.1 ± 2.8 years) performed steady isometric contractions with the knee flexors at four target torques (10%, 20%, 40%, and 60% of maximal voluntary contraction, MVC) at each of the three knee-joint angles (0°: long, 45°:...
Regional ecosystem responses to environmental drivers in cold‐water lakes evaluated using stable isotopes of salmonid fishesNARA Subscribed
Diverse environmental drivers influence food web energy and nutrient flows, a key ecosystem function, yet their relative importance remains poorly known. We compiled thousands of bulk stable isotope measurements (carbon and nitrogen) of brown trout ( Salmo trutta , n = 2854) and Arctic charr ( Salvelinus alpinus , n = 3062) from 120 cold‐water lakes across northern Europe, spanning 0.02 to 1090 km 2 in size, to quantify the re...