Protein translation is essential for maintaining the optimal functioning of the human nervous system. The 4E-Binding proteins (4E-BPs) are central regulators of this process, acting on the initiation factor eIF4E. Three homologs 4E-BP1, 4E-BP2, and 4E-BP3, are differentially expressed, with the phosphorylation state controlling cap-dependent translation in response to diverse physiological inputs, including growth factors, cyt...

Elasmobranchs are particularly vulnerable to overexploitation and population depletion, especially due to their life‐history traits, such as low reproductive output and slow growth. Given that capture‐induced parturition (abortion or premature birth) is a common consequence of fisheries in elasmobranchs, but still little studied, we investigated how the abortion/premature birth process varies in response to reproductive traits...

Berry's Creek is an urban tidal estuary of the Hackensack River (New Jersey, U.S.A.), with over 10 km of waterways and over 3 km 2 of tidal marsh. More than a century of industrial activity has resulted in elevated contaminant concentrations in sediment, water, and biota. Mercury, methyl mercury, and polychlorinated biphenyls (PCBs) have been identified as the primary chemicals of concern (COCs) due to their persistence and bi...

Changes in both global and regional mean sea level, and changes in the magnitude of extreme flood heights, are the result of a combination of several distinct contributions most, but not all, of which are associated with climate change. These contributions include effects in the solid earth, gravity field, changes in ocean mass due to ice loss from ice sheets and glaciers, thermal expansion, alterations in ocean circulation dr...