G. Walker results 298
· Newest (Page 1/12, per page 25)
Author: G. Walker ×Clear All Filters
Search Results
Residential gardens provide significant opportunities for biodiversity conservation. They cover substantial portions of urban landscapes, and it is well-established that wildlife species respond to specific habitat characteristics of residential gardens such as vegetation structure. However, wildlife responses to the full suite of landscaping decisions comprising the intentional creation of a garden for wildlife are less well-...
Interpretable deep learning reveals spatiotemporal MRI features of brain aging that align with neurodegenerationNARA Subscribed
Cortical thinning and atrophy are hallmarks of brain aging that have been characterized using magnetic resonance imaging (MRI). Brain aging involves many neuroanatomic features whose effects on brain structure remain unexplored. To address this challenge, we trained interpretable deep neural networks (DNNs) to estimate brain age (BA) from T 1 -weighted ( T 1 w) MRI. By identifying MRI features unapparent to humans, DNNs can fi...
Sex-specific associations of low-level urinary albumin-creatinine ratio with mortality and adverse cardiac events in older adultsNARA Subscribed
Albuminuria is traditionally defined using fixed urinary albumin–creatinine ratio (UACR) thresholds, although cardiovascular disease (CVD) risk has been reported to increase continuously across the UACR spectrum. Whether these associations are present in healthy older adults and differ by sex remains unclear. We examined sex-specific associations between low-level UACR, mortality, and cardiovascular outcomes in older adults wi...
Alzheimer’s disease (AD) disproportionately affects women and carriers of the apolipoprotein E ε4 allele (APOE4), yet little is known about how sex and APOE interact to influence white matter (WM) integrity during disease progression. We integrated diffusion MRI and matched blood transcriptomic data to investigate these interactions and their underlying biological mechanisms. WM microstructure was quantified using diffusion te...
The germline MLH1 c.-42 C > T (rs41285097) promoter variant has been identified in cases with MLH1-deficient colorectal or endometrial cancers but remains a variant of uncertain significance. Genetic testing identified two new MLH1 c.-42 C > T index cases from Australia and the USA. Clinicopathologic and molecular characterisation of tumour and non-neoplastic tissues was performed to investigate the potential mechanism of path...
Permafrost Thaw Accelerates Old Soil Carbon Release, Outpacing New Plant Inputs During a 13‐Year Tundra Warming ExperimentNARA Subscribed
Massive stores of ancient soil organic carbon (SOC) in permafrost can decompose with Arctic warming and accelerate global climate change. Declining SOC stocks are central to the permafrost carbon feedback, but direct measures of SOC loss are extremely rare due to methodological challenges related to subsidence in the Arctic. To fully capture changing SOC dynamics during thaw, we directly measured SOC stock and bulk soil radioc...
In order to investigate how shellfish culture in the intertidal zone may serve as a means of conferring resilience prior to subtidal deployment for commercial grow-out, a common garden experiment was carried out with juvenile Pacific oysters. Individuals were cultured under intertidal or subtidal conditions for one year, following which intertidal animals were transplanted to the subtidal site and both treatment groups were cu...
Three biogeochemical glider surveys in the Ross Sea between 2010 and 2023 were combined and analysed to assess production–export stock and rate dynamics. As the most productive of any Antarctic continental shelf, the Ross Sea is a site of substantial physical and biogeochemical interest. While this region and its annual bloom have been characterised for decades, logistical constraints, such as ship time and sea ice cover, have...
Stony coral tissue loss disease (SCTLD) has spread throughout Florida’s Coral Reef, causing extensive mortality of over 30 species of reef-building corals, and has rapidly spread to many other countries and territories throughout the Caribbean. Current treatments for SCTLD, including a proprietary paste mixed with the antibiotic amoxicillin, do not provide protection from future infections and may select for antibiotic-resista...