G. Warr results 15
· Newest (Page 1/1, per page 25)
Author: G. Warr ×Clear All Filters
Search Results
Prolonging survival in good health is a fundamental societal goal. However, the leading determinants of disability-free survival in healthy older people have not been well established. Data from ASPREE, a bi-national placebo-controlled trial of aspirin with 4.7 years median follow-up, was analysed. At enrolment, participants were healthy and without prior cardiovascular events, dementia or persistent physical disability. Disab...
The transcriptomic responses of the eastern oyster, Crassostrea virginica , to environmental conditionsNARA Subscribed
Understanding the mechanisms by which organisms adapt to environmental conditions is a fundamental question for ecology and evolution. In this study, we evaluate changes in gene expression of a marine mollusc, the eastern oyster Crassostrea virginica , associated with the physico‐chemical conditions and the levels of metals and other contaminants in their environment. The results indicate that transcript signatures can effecti...
A transcriptomic analysis of the stress induced by capture–release health assessment studies in wild dolphins ( Tursiops truncatus )NARA Subscribed
The health of wild bottlenose dolphins ( Tursiops truncatus ) is typically evaluated by the study of animals that are captured and released back into the wild after examination. The impact of such studies on gene expression in peripheral blood cells was investigated using microarray and quantitative polymerase chain reaction methods. Significantly increased expression was observed in two major classes of genes: (i) energy meta...
Comparative genomics of transcription factors driving expression of the immunoglobulin heavy chain locus in teleost fishNARA Subscribed
The immunoglobulin heavy chain locus of teleost fish is driven by an enhancer (Eμ3′) that contains, in all species examined, octamer and E‐box motifs (typically μE5). Thus, the transcription factors known (through experiments in fish) or predicted (from knowledge of their mammalian homologues) to be involved in the function of the enhancer are the octamer‐binding (Oct) transcription factors Oct1 and Oct2, their coactivator BOB...
Effects of cecropin peptides on bacteria pathogenic to fishNARA Subscribed
The antibacterial effects of synthetic cecropin B and cecropin P1 were tested against the fish‐pathogenic bacteria Vibrio anguillarum, Vibrio salmonicida, Aeromonas salmonicida , Edwardsiella ictaluri and Yersinia ruckeri. Both cecropins were active against all bacteria tested, but the effect was strongly influenced by the growth media used. In brain heart infusion medium, the minimum inhibitory concentrations of cecropin B ra...
Functional motifs in the IgH enhancer of the channel catfishNARA Subscribed
Previous1Next