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NARA Subscribed1
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Springer Nature1
Journal
Clinical & Experimental Metastasis1
Publication Year
20231
Geert C. van Almen results 1 · Newest (Page 1/1, per page 25)
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Treating colorectal peritoneal metastases with an injectable cytostatic loaded supramolecular hydrogel in a rodent animal modelNARA Subscribed
Clinical & Experimental Metastasis · 2023 · Vol. 40 · Issue 3 · Springer
Anne G. W. E. Wintjens; Hong Liu; Peter-Paul K.H. Fransen; Kaatje Lenaerts; Geert C. van Almen; Marion J. Gijbels; M’hamed Hadfoune; Bas T.C. Boonen; Natasja G. Lieuwes; Rianne Biemans; Ludwig J. Dubois; Patricia Y.W. Dankers; Ignace H.J.T. de Hingh; Nicole D. Bouvy
Patients with peritoneal metastases (PM) of colorectal cancer have a very poor outcome. Intraperitoneal delivery of chemotherapy is the preferred route for PM treatment. The main limitation of the treatment options is the short residence time of the cytostatic, with subsequent short exposure of the cancer cells. To address this, a supramolecular hydrogel has been developed that allows both local and slow release of its encapsu...
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