Cisplatin (Cis) has been widely used for treating many types of solid tumors. Despite its clinical effectiveness, Cis has a considerable risk of gonadal damage that may cause infertility. Morin hydrate (MH), a natural bioflavonoid, has been known for its antioxidant and anti-inflammatory effects. Our study aimed to investigate whether pretreatment with MH could protect against Cis-induced testicular toxicity. Thirty-five adult...

Stroke is a medical emergency that is associated with substantial mortality and functional disability in adults. The most popular class of antidepressants, selective serotonin reuptake inhibitors SSRIs, have recently been shown in studies to have positive effects on post-stroke motor and cognitive function. Thus, we hypothesized that dapoxetine (DAP), a short-acting SSRI, would be effective against cerebral ischemia/reperfusio...