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The decarbonization of shipping and the transformation towards digitally assisted or automated ship operation require new methods to analyze, predict, and optimize energy demand during maneuvering. The SimPleShip-SigMa sub-project of Hochschule Wismar developed and validated a comprehensive simulation-based framework combining real-time capable fast-time simulation of ship motion, detailed thermodynamic engine modeling, and hy...
The AD 365 and the AD 1303 tsunamis are known extreme wave events that caused severe damage and fatalities along the coastlines of the eastern Mediterranean Sea. We analysed geomorphological and sedimentological data from the Korission Lagoon (Corfu Island, Greece) and compared them with results of numerical simulations. Washover fans and sediment cores reveal coarse-grained high-energy deposits intersecting prevailing lagoona...
Habitat and space use of the garden dormouse (Eliomys quercinus) in urban and forest habitats in GermanyNARA Subscribed
The garden dormouse (Eliomys quercinus) inhabits a wide range of habitats, from urban areas in warm temperate lowlands to cool mountain ranges. Despite its adaptability, it has largely disappeared from its former range. While most forest populations in Germany are declining, some populations in cities remain stable. To better understand the ecology of this endangered species, VHF telemetry studies were conducted. Between May a...
The Mediterranean is particularly sensitive to rapid climate changes (RCCs) during the Holocene. An increasing number of natural climate archives revealed that socio‐economic developments were influenced by such RCCs since the Palaeolithic. However, multi‐millennial and high‐resolution archives are still rare and often located in mountainous regions, where they do not represent environmental conditions close to human settlemen...
Impact of Hedgehog modulators on signaling pathways in primary murine and human hepatocytes in vitro: insights into liver metabolismNARA Subscribed
The Hedgehog (Hh) signaling pathway is essential for maintaining homeostasis during embryogenesis and in adult tissues. In the liver, dysregulation of this pathway often leads to liver cancer development. Recent studies also suggest that disturbances in the Hh pathway can affect liver metabolism in healthy livers through interactions with other signaling pathways, such as the Wnt/β-catenin pathway. As a result, the Hh pathway...
In the framework of the STIMTEC and STIMTEC-X hydraulic stimulation experiments at the Reiche Zeche mine, Freiberg (Germany), we installed acoustic emission (AE) sensors for the recording of picoseismicity both conventionally using pneumatic coupling and experimentally like a hydrophone, i.e. the sensors were placed in the borehole without a further coupling system or cementing. We investigate performance measures of the hydro...
Multiple convective storms within a single cyclone on SaturnNARA Subscribed
The goal of this study is to provide a universally applicable procedure for a systematic evaluation of in situ measured data from single sensors regarding quantifying the uncertainty of the measurement results. As determining uncertainty for an environmental parameter also depends on the parameter itself, the focus here will be set on the variable water temperature in the first place. A separate analysis for salinity and other...
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and DevelopmentNARA Subscribed
Purpose More than 15 years have passed since the first description of the unbound brain-to-plasma partition coefficient (K p,uu,brain ) by Prof. Margareta Hammarlund-Udenaes, which was enabled by advancements in experimental methodologies including cerebral microdialysis. Since then, growing knowledge and data continue to support the notion that the unbound (free) concentration of a drug at the site of action, such as the brai...
Anthropogenic underwater noise has been identified as one of the main pressures on the marine environment. Considerable research efforts have been made to quantify acoustic soundscapes on different spatial and temporal scales in order to identify trends and investigate how this may impact the marine environment. Measures to reduce noise input into the seas from anthropogenic sources are under discussion, including the reductio...
Organizational and technical approaches have proven successful in increasing the performance and preventing risks at socio-technical systems at all scales. Nevertheless, damaging events are often unavoidable due to a wide and dynamic threat landscape and enabled by the increasing complexity of modern systems. For overall performance and risk control at the system level, resilience can be a versatile option, in particular for r...
Island biodiversity has long fascinated biologists as it typically presents tractable systems for unpicking the eco‐evolutionary processes driving community assembly. In general, two recurring themes are of central theoretical interest. First, immigration, diversification, and extinction typically depend on island geographical properties (e.g., area, isolation, and age). Second, predictable ecological and evolutionary trajecto...
Managing agricultural landscapes to support biodiversity and ecosystem services is a key aim of a sustainable agriculture. However, how the spatial arrangement of crop fields and other habitats in landscapes impacts arthropods and their functions is poorly known. Synthesising data from 49 studies (1515 landscapes) across Europe, we examined effects of landscape composition (% habitats) and configuration (edge density) on arthr...
Evolution of the latitudinal diversity gradient in the hyperdiverse ant genus PheidoleNARA Subscribed
Aim The latitudinal diversity gradient is the dominant geographic pattern of life on Earth, but a consensus understanding of its origins has remained elusive. The analysis of recently diverged, hyper‐rich invertebrate groups provides an opportunity to investigate latitudinal patterns with the statistical power of large trees while minimizing potentially confounding variation in ecology and history. Here, we synthesize global p...
Breaking out of biogeographical modules: range expansion and taxon cycles in the hyperdiverse ant genus PheidoleNARA Subscribed
Aim We sought to reconstruct the biogeographical structure and dynamics of a hyperdiverse ant genus, Pheidole, and to test several predictions of the taxon cycle hypothesis. Using large datasets on Pheidole geographical distributions and phylogeny, we (1) inferred patterns of biogeographical modularity (clusters of areas with similar faunal composition), (2) tested whether species in open habitats are more likely to be expandi...