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Maize inter-row weed management with a living mulch systemNARA Subscribed
The NeuroWES project: lessons learned from comprehensive phenotyping and genetic analysis of neurodevelopmental disorders over a decadeNARA Subscribed
Exome sequencing (ES) has become a primary tool for diagnosing neurodevelopmental disorders (NDDs), yet the interpretation of genetic variants in large, heterogeneous cohorts presents significant challenges that automated pipelines often fail to resolve. This study showcases the complexities and novel findings derived from a decade-long analysis of 419 Italian NDD patient-parent trios. While ES established a molecular diagnosi...
Label-free proteomic profiling identifies ECM-related alterations across regeneration states in human peripheral axonal neuropathiesNARA Subscribed
Understanding the multiple mechanisms underlying peripheral nerve regeneration in humans is crucial for developing effective therapies for peripheral axonal neuropathies. Although i n vitro and in vivo studies have provided significant insights, human studies exploring the composition of proteome remain limited. The ECM plays a crucial role in nerve regeneration, influencing cell adhesion, proliferation, migration, and finally...
Meat products represent important vehicles for foodborne viral transmission, yet standardized detection methodologies for these complex matrices remain limited. This study systematically compared three viral recovery methods across nine meat products representing chicken, pork, and processed deli meat matrices: polyethylene glycol 6000 (PEG) precipitation, glycine buffer-chloroform (GBC) phase separation, and β-mercaptoethanol...