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This study presents field measurements for a non-conventional mobile square cylinder fish enclosure, with permeable ends, evaluated under both towed and moored conditions at a semi-open ocean test site. Novelty lies within the enclosure design that enables both mobility and control of internal flow through the incorporation of an adjustable aft-end perimeter constriction to regulate internal flow and support fish welfare by en...
Marine megafauna species are affected by a wide range of anthropogenic threats. To evaluate the risk of such threats, species’ vulnerability to each threat must first be determined. We build on the existing threats classification scheme and ranking system of the International Union for Conservation of Nature (IUCN) Red List of Threatened Species by assessing the vulnerability of 256 marine megafauna species to 23 at‐sea threat...
The Toxicology Investigators Consortium 2024 Annual ReportNARA Subscribed
Impacts of Antibody Structure and Mixtures on Receptor Signaling for Antibody-Dependent Cellular CytotoxicityNARA Subscribed
Antibody-Dependent Cellular Cytotoxicity (ADCC) is a key mechanism of action for humoral immune response, which is important for clinical antibodies such as trastuzumab and cetuximab. The level of ADCC is dependent on multiple properties such as antibody isotype, Fab affinity, epitope, and geometry in the immune synapse. Here, we integrated computational simulations with experiments to analyze the impacts of several key factor...
Testing the incorporation of bioassays into life cycle assessment: A case study on advanced wastewater treatmentNARA Subscribed
Purpose Advanced wastewater treatment (AWT) methods, such as the use of ozone (O 3 ) and granular activated carbon (GAC), have been shown to mitigate toxic impacts on receiving waters. However, life cycle assessments (LCAs) on AWT technologies commonly evaluate toxicity through chemical analysis and conclude that the increased toxicity caused by operational inputs exceeds the reduction in toxicity via micropollutant removal fr...
Bryde's whale ( Balaenoptera edeni ) occurrence and foraging behaviour along the east coast of AustraliaNARA Subscribed
Despite their global occurrence in warm‐temperate waters and their suspected non‐migratory lifestyle, Bryde's whales ( Balaenoptera edeni spp.) are considered the least‐known large baleen whale species. In Australian waters, information on their distribution, ecology and behaviour is scarce. This study documents Bryde's whale occurrence and foraging behaviours along the Australian East Coast using opportunistic citizen science...
Environmental and Geographic Conditions on the Breeding Grounds Drive Bergmannian Clines in NightjarsNARA Subscribed
Aim To evaluate (1) whether three migratory nightjar species (Family Caprimulgidae) adhere to Bergmann's rule, (2) whether environmental factors on the breeding or wintering grounds determine body size, and (3) which mechanistic hypotheses best explain Bergmannian patterns in body size. Location North and South America; Europe and Africa. Taxon Eastern whip‐poor‐will ( Antrostomus vociferus ), Common nighthawk ( Chordeiles min...
Monitoring Estuarine Habitats and Threats at a Regional Scale Using Aerial Photography, Object-Based Image Analysis and Deep LearningNARA Subscribed
Estuarine macrophytes, including seagrass, mangrove, and saltmarsh species, are ecological foundation species that significantly influence biodiversity, ecosystem processes, and provide various cultural and economic benefits. These habitats are, however, facing numerous threats from human disturbances which operate over a range of spatial and temporal scales. Effective management of estuarine macrophytes requires an understand...
Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory declineNARA Subscribed
Longitudinal investigation of the Apolipoprotein E (APOE) genotype’s impact on Alzheimer’s disease (AD) biomarker progression, focusing on amyloid beta (Aβ) accumulation and gray matter (GM) atrophy, integrating cognitive decline and baseline levels. Longitudinal florbetapir-PET and T1-weighted MRI data from 100 cognitively normal (CN) and mild cognitive impaired (MCI) participants both with considerable global Aβ accumulation...
Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia predictionNARA Subscribed
DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of cognitive impairment and future dementia risk using the ADNI database. Of several MA algorithms, DunedinPACE and GrimAge2, associated with memory, were combined in a composite MA alongside BA and a data-driven FI in predictive analyse...
The Toxicology Investigators Consortium 2023 Annual ReportNARA Subscribed
The use of plant genetic resources (PGR)—wild relatives, landraces, and isolated breeding gene pools—has had substantial impacts on wheat breeding for resistance to biotic and abiotic stresses, while increasing nutritional value, end‐use quality, and grain yield. In the Global South, post‐Green Revolution genetic yield gains are generally achieved with minimal additional inputs. As a result, production has increased, and milli...
The gold rush at the end of the nineteenth century in south-eastern Australia resulted in the mobilization and re-deposition of vast quantities of tailings that modified the geomorphology of the associated river valleys. Previous studies of contamination risk in these systems have either been performed directly on mine wastes (e.g., battery sand) or at locations close to historical mine sites but have largely ignored the exten...