As the world's population grows, aquaculture is becoming a rapidly growing source of protein. Grass carp ( Ctenopharyngodon idella ) is one of the most important aquacultured species in China and has emerged as a significant commercial fish worldwide. However, grass carp reovirus (GCRV) poses a significant threat to grass carp aquaculture. This review covers GCRV biology, phylogeny, pathogenesis, immune response pathways, ther...

Cell line misidentification or contamination undermines the reliability of research outcomes. In this study, we verified the species origin of commonly used fish cell lines, with a particular focus on the grass carp ovarian cell line (GCO). RNA‐seq data from 146 samples of 11 widely used fish cell lines were collected from public databases (NCBI‐SRA) and were mapped to the reference genomes of eight species. GCO RNA‐seq sample...

The expansion of marine economic activities and the increasing demand for maritime security have positioned drone-based aerial object detection as a crucial technology for applications such as marine environmental monitoring and maritime law enforcement. However, maritime aerial imagery remains highly challenging due extreme illumination variations, the small size and indistinct appearance of targets. This paper introduces a n...

Clinical investigations have suggested a potential link between cataracts and Alzheimer’s disease (AD). However, whether cataract has an impact on the progression of AD remains unclear. The objective of this research was to determine the relationship between cataracts and AD. A cataract model was established in APP/PS1 [mutant amyloid precursor protein (APP) and a mutant presenilin-1 (PS1) gene] mice via lens puncture. Behavio...

Accurate timing of myelination is crucial for the proper functioning of the central nervous system. Here, we identified a de novo heterozygous mutation in TMEM63A (c.1894G>A; p. Ala632Thr) in a 7-year-old boy exhibiting hypomyelination. A Ca 2+ influx assay suggested that this is a loss-of-function mutation. To explore how TMEM63A deficiency causes hypomyelination, we generated Tmem63a knockout mice. Genetic deletion of TMEM63...