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miR-214-3p exacerbates mitochondrial dysfunction in parkinson's disease: a multi-omics and mechanistic studyNARA Subscribed
Parkinson’s disease (PD) involves the loss of dopaminergic neurons, and prodromal PD exhibits elevated miR-214-3p, suggesting its role as a biomarker and pathogenic factor. This study investigated miR-214-3p’s effects on mitochondrial function in dopaminergic SH-SY5Y cells and mouse primary cortical neurons. In SH-SY5Y cells, proteomic/transcriptomic analyses and target prediction confirmed GFM1 as a direct target of miR-214-3...
BarleyOmics: A comprehensive multi-omics database of barleyNARA Subscribed
Mycorrhizal dominance influences tree species richness and richness–biomass relationship in China's forestsNARA Subscribed
Mycorrhizal associations drive plant community diversity and ecosystem functions. Arbuscular mycorrhiza (AM) and ectomycorrhiza (EcM) are two widespread mycorrhizal types and are thought to differentially affect plant diversity and productivity by nutrient acquisition and plant–soil feedback. However, it remains unclear how the mixture of two mycorrhizal types influences tree diversity, forest biomass, and their relationship a...