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Realigning structural MR images to stereotactic AC-PC space is a standard procedure that enhances anatomical consistency both within and across neuroimaging studies, allowing for precise spatial localization and reliable cross-subject comparisons in both clinical and research contexts. However, different versions of AC-PC spaces, stemming from varying definitions of the AC-PC axis as outlined in common stereotactic atlases lik...
Formation and persistence of estragole-derived DNA adducts in human liver cells and tissueNARA Subscribed
Estragole (ES) is a phenylpropene naturally occurring in various herbs and spices, such as fennel and basil. Humans are exposed to ES via the diet or herbal medicinal products. Following its gastrointestinal resorption, hepatic bioactivation of ES by Cytochrome P450 monooxygenases (CYPs) and sulfotransferases (SULTs) can lead to DNA adduct formation and liver cancer in rodents. Up to now, no data is available on ES-dependent D...
Functional and vascular neuroimaging in maritime pilots with long-term sleep disruptionNARA Subscribed
The mechanism underlying the possible causal association between long-term sleep disruption and Alzheimer’s disease remains unclear Musiek et al. 2015. A hypothesised pathway through increased brain amyloid load was not confirmed in previous work in our cohort of maritime pilots with long-term work-related sleep disruption Thomas et al. Alzheimer’s Res Ther 2020;12:101. Here, using functional MRI, T2-FLAIR, and arterial spin l...
Sperm whales exhibit variation in echolocation tactics with depth and sea state but not naval sonar exposuresNARA Subscribed
Auditory masking by anthropogenic noise may impact marine mammals relying on sound for important life functions, including echolocation. Animals have evolved antimasking strategies, but they may not be completely effective or cost‐free. We formulated seven a priori hypotheses on how odontocete echolocation behavior could indicate masking. We addressed six of them using data from 15 tagged sperm whales subject to experimental e...
TRY plant trait database – enhanced coverage and open accessNARA Subscribed
Plant traits—the morphological, anatomical, physiological, biochemical and phenological characteristics of plants—determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodivers...
Conventional land‐use intensification reduces species richness and increases production: A global meta‐analysisNARA Subscribed
Most current research on land‐use intensification addresses its potential to either threaten biodiversity or to boost agricultural production. However, little is known about the simultaneous effects of intensification on biodiversity and yield. To determine the responses of species richness and yield to conventional intensification, we conducted a global meta‐analysis synthesizing 115 studies which collected data for both vari...
Similarities in butterfly emergence dates among populations suggest local adaptation to climateNARA Subscribed
Phenology shifts are the most widely cited examples of the biological impact of climate change, yet there are few assessments of potential effects on the fitness of individual organisms or the persistence of populations. Despite extensive evidence of climate‐driven advances in phenological events over recent decades, comparable patterns across species' geographic ranges have seldom been described. Even fewer studies have quant...
Modeling Effectiveness of Gradual Increases in Source Level to Mitigate Effects of Sonar on Marine MammalsNARA Subscribed
Ramp‐up or soft‐start procedures (i.e., gradual increase in the source level) are used to mitigate the effect of sonar sound on marine mammals, although no one to date has tested whether ramp‐up procedures are effective at reducing the effect of sound on marine mammals. We investigated the effectiveness of ramp‐up procedures in reducing the area within which changes in hearing thresholds can occur. We modeled the level of soun...