All Articles results 42
· Newest (Page 1/2, per page 25)
Author: H. Schindler ×Clear All Filters
Search Results
Rationale The potent synthetic opioid fentanyl, and its analogs, continue to drive opioid-related overdoses. Although the pharmacology of fentanyl is well characterized, there is little information about the reinforcing effects of clandestine fentanyl analogs (FAs). Objectives Here, we compared the effects of fentanyl and the FAs acetylfentanyl, butyrylfentanyl, and cyclopropylfentanyl on drug self-administration in male and f...
This systematic review examines the prevalence, underlying mechanisms, cohort characteristics, evaluation criteria, and cohort types in white matter hyperintensity (WMH) pipeline and implementation literature spanning the last two decades. Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, we categorized WMH segmentation tools based on their methodologies from January 1, 2000, to...
Developing a list of invasive alien species likely to threaten biodiversity and ecosystems in the European UnionNARA Subscribed
The European Union ( EU ) has recently published its first list of invasive alien species ( IAS ) of EU concern to which current legislation must apply. The list comprises species known to pose great threats to biodiversity and needs to be maintained and updated. Horizon scanning is seen as critical to identify the most threatening potential IAS that do not yet occur in Europe to be subsequently risk assessed for future listin...
Signals of heterogeneous selection at an MHC locus in geographically proximate ecotypes of sockeye salmonNARA Subscribed
The genes of the major histocompatibility complex ( MHC ) are an important component of the vertebrate immune system and can provide insights into the role of pathogen‐mediated selection in wild populations. Here, we examined variation at the MHC class II peptide‐binding region in 27 populations of sockeye salmon ( Oncorhynchus nerka ), distributed among three distinct spawning ecotypes, from a complex of interconnected rivers...
We explore the role of lakes in carbon cycling and global climate, examine the mechanisms influencing carbon pools and transformations in lakes, and discuss how the metabolism of carbon in the inland waters is likely to change in response to climate. Furthermore, we project changes as global climate change in the abundance and spatial distribution of lakes in the biosphere, and we revise the estimate for the global extent of c...
Disrupted seasonal clockwork in the population dynamics of a freshwater copepod by climate warmingNARA Subscribed
Life history responses are expected to accompany climate warming, yet little is known how long‐term effects of climate and environmental change affect the seasonal dynamics of planktonic organisms. We used an historical data set from Lake Washington (U.S.A.) to quantify population responses of a calanoid copepod ( Leptodiaptomus ashlandi ) to long‐term changes in temperature and resource availability and explore potential mech...
Rapid loss of biodiversity worldwide has raised concerns about the consequences to ecosystem functioning, including processes such as litter decomposition. Consequent experiments with litter mixtures to assess effects of changing tree composition and diversity on decomposition have given mixed results, but the causes are not clear. Reasoning that such conflicting accounts reported in the literature may be reconciled by conside...