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Pharmacokinetics and Withdrawal Time of Doxycycline in Snakehead ( Channa striata ) Following Oral MedicationNARA Subscribed
The study consisted of two experiments. First, a PK experiment was set up with a single oral dose at 20 mg/kg body weight, and second, a withdrawal time determination study, where the fish were fed once a day for 5 consecutive days at the same dosage. The DOX concentration in medicated feed, fish muscle, plasma, liver, and kidney was analysed by LC–MS/MS. Phoenix 8.1 and WT 1.4 software were used in the calculation for PK para...
The HOMER2 gene, crucial for synaptic signaling and calcium homeostasis in the auditory system, is linked to sensorineural hearing loss (SNHL), with its variants contributing to severe SNHL in older adults, often necessitating cochlear implants in their 60 s or 70 s. In this study, we identified a novel frameshift extension variant, c.1033delC (p.Arg345Glu fs *64; p.R345E fs *64), which introduces a significantly longer protei...
Dominance and rarity in tree communities across the globe: Patterns, predictors and threatsNARA Subscribed
Aim Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation management it is important to understand the drivers of dominance and rarity in local tree communities. We answer the following research questions: (1) What are the patterns of dominance and rarity in tree...