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Genetic and immunological determinants of Pemphigus vulgaris: integrative analysis of HLA-DRB1 and FCGR2B variantsNARA Subscribed
Pemphigus vulgaris (PV) is a rare autoimmune blistering disease mediated by pathogenic autoantibodies. Although both HLA and non-HLA loci contribute to disease susceptibility, their combined roles in immune regulation remain incompletely understood. This study investigated the joint contribution of HLA-DRB1 and FCGR2B variants to PV susceptibility within an integrative immunogenetic framework. Genotype data from 286 individual...
Polyethylene terephthalate (PET) is one of the most widely used thermoplastic materials in the world, commonly found in packaging, textiles, and bottles. However, its persistence in the environment has become a significant global concern due to the growing accumulation of plastic waste. While various strategies for PET degradation have been proposed, none have yet been successfully adopted at an industrial scale. Nonetheless,...
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