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Heejun Shin results 3 · Newest (Page 1/1, per page 25)
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Journal of Pharmaceutical Investigation · 2018 · Vol. 48 · Issue 2 · Springer
Photodynamic therapy (PDT) is performed using a photosensitizer and light of specific wavelength in the presence of oxygen to generate singlet oxygen and reactive oxygen species(ROS) in the cancer cells. The accumulated photosensitizers in target sites induce ROS generation upon light activation, then the generated cytotoxic reactive oxygen species lead to tumor cell death via apoptosis or necrosis, and damages the target site...