Autism spectrum disorder (ASD) is a neurological disorder associated with brain inflammation. The underlying mechanisms could be attributed to the activation of PI3K signaling in the inflamed brain of ASD. Multiple studies highlight the role of GRPR in regulating ASD like abnormal behavior and enhancing the PI3K signaling. However, the molecular mechanism by which GRPR regulates PI3K signaling in neurons of individuals with AS...

Understanding historical droughts in northern China is challenging due to the limited time records of meteorological stations. In this study, we reconstructed the precipitation variability in the middle Taihang Mountains over 414 years by using the tree‐ring width of Pinus tabulaeformis . Based on our climate response analysis, Pinus tabulaeformis growth at the sampling sites was mainly restricted by the total precipitation fr...

Background and purpose Efforts to improve nurses’ physical and mental health are critical to ensuring the safety and quality of the healthcare system. Long-term studies targeting the relevancy of nurses’ occupation characteristics with health conditions remain insufficient. This study aimed to examine the relationship between nurses’ night shift and sleep problems and metabolic abnormalities risk. Methods This study was a part...